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PDE3A - Gene Detail

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Gene Symbol PDE3A
Synonyms CGI-PDE | CGI-PDE A | CGI-PDE-A | HTNB
Gene Description PDE3A, phosphodiesterase 3A, encodes a cGMP-inhibited cyclic nucleotide phosphodiesterase that plays diverse roles in cellular function including oocyte maturation (PMID: 11988323), vascular function (PMID: 22051884), and apoptosis (PMID: 32591543). Overexpression of Pde3a has been identified in breast cancer (PMID: 31871268), gastrointestinal stromal tumor (PMID: 30530703), and hepatocellular carcinoma (PMID: 29425759).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
5139 12 12p12.2 NM_000921 Unknown
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