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DDX41 - Gene Detail

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Gene Symbol DDX41
Synonyms ABS | MPLPF
Gene Description DDX41, DEAD-box helicase 41, encodes an SF2 superfamily member that plays a role in innate immunity, and has putative involvement in mRNA splicing and post-transcriptional regulation (PMID: 27502187, PMID: 28547672). DDX41 mutations, both somatic and germline, are associated with myeloid neoplasms including myelodysplastic syndrome and acute myeloid leukemia (PMID: 25920683, PMID: 31484648).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
51428 5 5q35.3 NM_016222 Unknown
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