Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | PDE4D | ||||||||||
| Synonyms | ACRDYS2 | DPDE3 | HSPDE4D | PDE43 | PDE4DN2 | STRK1 | ||||||||||
| Gene Description | PDE4D, phosphodiesterase 4D, is a cyclic nucleotide phosphodiesterase that regulates cAMP degradation (PMID: 16968949). Overexpression of Pde4d has been observed in a variety of cancers (PMID: 23536305), including pancreatic ductal carcinoma (PMID: 31772658) and melanoma (PMID: 28092671), decreased Pde4d expression has been demonstrated in bladder cancer (PMID: 30482227), and a PDE4D-CCNB1 fusion has been identified in ovarian endometrioid ovarian carcinoma (PMID: 29633253). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
