Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol SIRT6
Synonyms hSIRT6 | SIR2L6
Gene Description SIRT6, sirtuin 6, is a member of the sirtuin family of proteins that acts as both deacetylase and mono-ADP ribosyltransferase, and is involved in diverse cellular processes including DNA repair, inflammation, apoptosis, proliferation, metabolism, and aging (PMID: 26717993). Dysregulation of Sirt6 expression has been identified in a variety of solid tumors and hematological cancers (PMID: 26717993).
Additional content available in CKB BOOST