Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol PDGFB
Synonyms c-sis | IBGC5 | PDGF-2 | PDGF2 | SIS | SSV
Gene Description PDGFB, platelet derived growth factor subunit B, is a growth factor that signals through PDGFRs and plays a role in regulation of development, cell proliferation, cell migration (PMID: 18483217), and angiogenesis (PMID: 32235327). Overexpression of PDGFB has been implicated in several tumor types (PMID: 24359404), including oral squamous cell carcinoma (PMID: 32235327), and a fusion with COL1A1 has been reported in dermatofibrosarcoma protuberans (PMID: 31870844, PMID: 31353504).
Additional content available in CKB BOOST