HDAC7: Gene Detail - Cancer Knowledgebase (CKB)

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Gene Symbol

HDAC7

Synonyms

HD7 | HD7A | HDAC7A

Gene Description

HDAC7, histone deacetylase 7, is a member of the class IIa histone deacetylase family that regulates gene transcription (PMID: 35303381, PMID: 25244360), and plays a role in diverse biological processes including musculoskeletal system development (PMID: 11279209, PMID: 21324898, PMID: 17997710, PMID: 25389289), immune cell function (PMID: 12753745, PMID: 17369396, PMID: 23696748), and vascular integrity (PMID: 16873063). Increased HDAC7 expression has been reported in multiple tumor types (PMID: 38487728) including non-small cell lung cancer (PMID: 35277183), pancreatic adenocarcinoma (PMID: 18506539), and high-grade gliomas (PMID: 30654849).

NCBI Gene ID	Chromosome	Map Location	Canonical Transcript	Gene Role
51564	12	12q13.11	NM_015401	Unknown

Additional content available in

CKB BOOST

Gene Variants 1
Category Variants 0
Molecular Profiles 1
Evidence 0
Clinical Trials 0

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The public access version, CKB CORE™, encompasses 50 cancer-related genes, and every quarter, a select group of genes are exchanged, focusing on a specific theme. Users can search CKB CORE™ via gene and gene variants. The web-based, subscription version, CKB BOOST™, includes more than 2000 cancer-related genes and is designed to interrogate the knowledgebase for specific data attributes while enabling a robust browse-like feature when the desired content is unknown.

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HDAC7 - Gene Detail

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