PDGFRL - Gene Detail

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Gene Symbol PDGFRL
Synonyms PDGRL | PRLTS
Gene Description PDGFRL, platelet derived growth factor receptor like, is involved in chondrocyte proliferation and differentiation (PMID: 28407304) and may function as a tumor suppressor, inhibiting cell proliferation and invasion (PMID: 20333786). PDGFRL mutations and loss of heterozygosity have been identified in prostate cancer (PMID: 9197531), and decreased expression of Pdgfrl has been observed in colorectal cancer (PMID: 20333786) and breast cancer (PMID: 16552773).
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