Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | PDGFRB | ||||||||||
| Synonyms | CD140B | IBGC4 | IMF1 | JTK12 | KOGS | PDGFR | PDGFR-1 | PDGFR1 | PENTT | ||||||||||
| Gene Description | PDGFRB, platelet derived growth factor receptor beta, is a receptor tyrosine kinase that plays a role in blood vessel development, cell proliferation, migration (PMID: 18483217, PMID: 20529858), and lymphangiogenesis (PMID: 31949689). PDGFRB fusions are associated with several tumor types (PMID: 24703957) and commonly found in myeloid neoplasms (PMID: 31999327, PMID: 31161074), while overexpression has been observed in metastatic non-small cell lung cancer (PMID: 31949689, PMID: 31308421) and somatic mutations in myofibroma (PMID: 31017643). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
