Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol ENPP3
Synonyms B10 | CD203c | NPP3 | PD-IBETA | PDNP3
Gene Description ENPP3, ectonucleotide pyrophosphatase/phosphodiesterase family member 3, is a basophil activation marker (PMID: 26589436) that hydrolyze nucleotides (PMID: 25692702) and nucleotide sugars, which may influence overall cellular glycosylation profiles (PMID: 23960081). Overexpression of Enpp3 has been observed in adrenocortical carcinomas (PMID: 29045509) and is a target for antibody-drug conjugates in refractory renal cell carcinoma (PMID: 29848572, PMID: 26589436).
Additional content available in CKB BOOST