Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol PIGA
Synonyms GPI3 | MCAHS2 | NEDEPH | PIG-A | PNH1
Gene Description PIGA, phosphatidylinositol glycan anchor biosynthesis class A, is an enzyme essential for biosynthesis of glycosyl-phosphatidyl inositol (GPI) anchors, which play a role in linking proteins to the cell surface (PMID: 8647522, PMID: 25885527, PMID: 28516949). PIGA mutations are associated with aplastic anemia (PMID: 27121470).
Additional content available in CKB BOOST