Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol BCL11A
Synonyms CTIP1 | DILOS | EVI9 | HBFQTL5 | SMARCM1 | ZNF856
Gene Description BCL11A, BCL11 transcription factor A, is a zinc finger transcription factor that primarily plays a role in transcriptional repression (PMID: 32625084), with involvement in lymphoid development (PMID: 12717432) and the fetal to adult hemoglobin switch (PMID: 19056937, PMID: 19657335). Overexpression of BCL11A has been observed in natural killer/T-cell lymphoma (PMID: 32625084) and breast cancer (PMID: 31114347), including triple-negative breast cancer (PMID: 32218847), and a BCL11A-ALK fusion has been identified in lung adenocarcinoma (PMID: 31122560).
Additional content available in CKB BOOST