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Gene Symbol PML
Synonyms MYL | PP8675 | RNF71 | TRIM19
Gene Description PML, PML nuclear body scaffold, also known as promyelocytic leukemia is a nuclear phosphoprotein that is associated with cellular functions related to cell adhesion, differentiation, migration, and proliferation (PMID: 23555679). The PML-RARA oncogenic fusion is diagnostic for acute promyelocytic leukemia (PMID: 23555679, PMID: 32323584, PMID: 32182684, PMID: 31809670).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
5371 15 15q24.1 NM_033238 Tumor suppressor (PMID: 30606230)
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