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Gene Symbol | ING3 | ||||||||||
Synonyms | Eaf4 | ING2 | MEAF4 | p47ING3 | ||||||||||
Gene Description | ING3, inhibitor of growth family member 3, is a member of the NuA4 histone acetyl transferase complex (HAT), that plays a role in p53 mediated transcription, cell division, and apoptosis (PMID: 12545155, PMID: 16520380, PMID: 24066152). ING3 is associated with a number of cancers such as head and neck squamous cell carcinoma (PMID: 21052543) and prostate cancer (PMID: 28511652) and a fusion with BCOR has been reported in endometrial stromal sarcoma (PMID: 32156473). | ||||||||||
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