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Gene Symbol PPARG
Synonyms CIMT1 | GLM1 | NR1C3 | PPARG1 | PPARG2 | PPARG5 | PPARgamma
Gene Description PPARG, peroxisome proliferator-activated receptor gamma, is a transcription factor and member of the proliferator-activated receptor family of nuclear receptors and regulates adipocyte differentiation and glucose homeostasis (PMID: 9209705, PMID: 30651555). PPARG fusions are frequently observed with PAX8 in follicular thyroid carcinoma (PMID: 25069464) and missense mutations and amplification have been reported in luminal bladder cancer (PMID: 30651555).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
5468 3 3p25.2 NM_015869 Tumor suppressor (PMID: 30606230)
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