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Gene Symbol PPEF1
Synonyms PP7 | PPEF | PPP7C | PPP7CA
Gene Description PPEF1, protein phosphatase with EF-hand domain 1, is a serine-threonine phosphatase that contains an EF hand domain (PMID: 19662497) and may play a role in regulating Tp53 induction of apoptosis in response to genotoxic stress (PMID: 28051100). Overexpression of Ppef1 has been observed in colorectal, breast, prostate, liver, and lung cancers (PMID: 28051100).
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