Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol BCOR
Synonyms ANOP2 | MAA2 | MCOPS2
Gene Description BCOR, BCL6 corepressor, functions with B-cell CLL/lymphoma 6 (BCL6) as a transcriptional silencer (PMID: 10898795, PMID: 16943429) and also suppresses MLLT3 (AF9) transcriptional activity (PMID: 12776190). BCOR mutations from internal tandem duplication (ITD; PMID: 28687574) and loss of function mutations are commonly found in hematological cancers (PMID: 28827447) and are also found in retinoblastoma and sarcomas of the bone and kidney (PMID: 28827447).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
54880 X Xp11.4 NM_001123385 Tumor suppressor (PMID: 30606230)
Additional content available in CKB BOOST