Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol PPL
Synonyms
Gene Description PPL, periplakin, is a membrane-associated protein that functions in the formation of the cornified cell envelope in keratinocytes (PMID: 24942859). A PPL-NTRK1 fusion has been observed in thyroid carcinoma (PMID: 25384085) and loss of Ppl expression has been observed in colorectal carcinoma (PMID: 28068625) and urothelial carcinoma (PMID: 24942859).
Additional content available in CKB BOOST