Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | LRRC1 | ||||||||||
| Synonyms | dJ523E19.1 | LANO | ||||||||||
| Gene Description | LRRC1, leucine rich repeat containing 1, is a paralog of the tumor suppressor protein, SCRIB, that interacts with Maguk and Erbin proteins in epithelial cells (PMID: 11440998), and has been demonstrated to play a role in stem cell fate in mammary glands through the Wnt pathway (PMID: 30344009). Overexpression of LRRC1 has been identified in hepatocellular carcinoma (PMID: 23645086) and a fusion with TRAF has been identified in lung cancer (PMID: 30294322). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
