STEAP3 - Gene Detail

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Gene Symbol STEAP3
Synonyms AHMIO2 | dudlin-2 | dudulin-2 | pHyde | STMP3 | TSAP6
Gene Description STEAP3, STEAP3 metalloreductase, promotes reduction of iron and copper ions (PMID: 16609065), and is involved in iron uptake in erythroid cells (PMID: 16227996), iron homeostasis, and innate immunity (PMID: 22689674). Overexpression of Steap3 has been observed in various tumor types including ovarian cancer (PMID: 37386521), triple-negative breast cancer (PMID: 37064114), clear cell renal cell carcinoma (PMID: 36424540), and glioma (PMID: 39537233).
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