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Gene Symbol ETNK1
Synonyms EKI | EKI 1 | EKI1 | Nbla10396
Gene Description ETNK1, ethanolamine kinase 1, phosphorylates ethanolamine and initiates the biosynthesis of phosphatidylethanolamine (PMID: 11044454), which is a major phospholipid of the mammalian cell membrane and is involved in a variety of diseases (PMID: 28785375). ETNK1 mutations have been identified in systemic mastocytosis and chronic myeloid leukemia (PMID: 25615281, PMID: 25343957), and amplification of ETNK1 has been identified in testicular seminoma (PMID: 11912161) and lung adenocarcinoma (PMID: 31448219).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
55500 12 12p12.1 NM_018638 Tumor suppressor (PMID: 30606230)
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