Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol PRKAA2
Synonyms AMPK | AMPK2 | AMPKa2 | PRKAA
Gene Description PRKAA2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, is a catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PMID: 24895169). Prkaa2 loss of function mutations have been identified in some cancers (PMID: 26934201) and Ube2o ubiquitination of Prkaa2 promotes tumor growth in mice (PMID: 28162974).
Additional content available in CKB BOOST