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Gene Symbol | NHP2 | ||||||||||
Synonyms | DKCB2 | NHP2P | NOLA2 | ||||||||||
Gene Description | NHP2, NHP2 ribonucleoprotein, is a component of the telomerase ribonucleoprotein complex, which plays a role in telomere maintenance and the maturation of ribosomal RNA and small nuclear RNA (PMID: 37440454, PMID: 18523010), and is potentially involved in DNA damage response at telomeres (PMID: 33595114). Increased expression of Nhp2 has been identified in gastric cancer (PMID: 22935986) and colorectal cancer (PMID: 22935986, PMID: 34129943) while decreased expression has been identified in endometrial cancer (PMID: 35054812). | ||||||||||
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