Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol ATF7IP
Synonyms AM | ATF-IP | ATF7IP1 | MCAF | MCAF1 | p621
Gene Description ATF7IP, activating transcription factor 7 interacting protein, is an epigenetic regulator and transcriptional cofactor that can act as an activator or repressor (PMID: 19106100), and functions in the regulation of SETDB1 activity (PMID: 31576654), formation of H3K9me3, and Th17 differentiation (PMID: 31217192). An ATF7IP-JAK2 fusion has been observed in acute lymphoblastic leukemia (PMID: 25207766) and an ATF7IP-PDGFRB fusion has been observed in acute lymphoblastic leukemia (PMID: 29133777).
Additional content available in CKB BOOST