Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol PRKAR1A
Synonyms ACRDYS1 | ADOHR | CAR | CNC | CNC1 | PKR1 | PPNAD1 | PRKAR1 | Prkar1alpha | TSE1
Gene Description PRKAR1A, protein kinase cAMP-dependent type I regulatory subunit alpha, is a major component of Pka which mediates cAMP-dependent signaling (PMID: 26042218). Inactivation of PRKAR1A is associated with the familial syndrome of Carney complex (PMID: 20301463, PMID: 30699069), adrenocortical tumors (PMID: 26042218), and melanoma (PMID: 32118628).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
5573 17 17q24.2 NM_212472 Both: Oncogene and Tumor suppressor (PMID: 30606230)
Additional content available in CKB BOOST