CDC50A - Gene Detail

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Gene Symbol CDC50A
Synonyms C6orf67 | TMEM30A
Gene Description CDC50A, cell division cycle 50 P4-ATPase accessory subunit A, forms the accessory subunit of the flippase complex that promotes proper folding and functioning of the P4-ATPase, and plays a role in aminophospholipid transport across cell membranes, ensuring asymmetrical distribution, which is necessary for key cellular functions (PMID: 27458383, PMID: 19780638). Mutations in CDC50A have been identified in diffuse large B-cell lymphoma (PMID: 32094924).
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