CMTR2 - Gene Detail
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| Gene Symbol | CMTR2 | ||||||||||||
| Synonyms | AFT | FTSJD1 | HMTr2 | MTr2 | ||||||||||||
| Gene Description | CMTR2, cap methyltransferase 2, methylates the 2'-O-ribose of the second nucleotide within the 5' cap of mRNA and snRNA (PMID: 21310715), and plays a role in early embryonic development (PMID: 39094818, PMID: 37436893) and innate immune response evasion (PMID: 38325897, PMID: 36018811). Mutations in CMTR2 have been identified in lung adenocarcinoma (PMID: 27158780). | ||||||||||||
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