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AXL - Gene Detail

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Gene Symbol AXL
Synonyms ARK | AXL3 | JTK11 | Tyro7 | UFO
Gene Description AXL, AXL receptor tyrosine kinase, is a receptor tyrosine kinase, which promotes growth, migration, and survival of tumor cells through activation of Mapk signaling (PMID: 28072762). Activation and overexpression of AXL has been associated with resistance to chemotherapeutic agents and targeted therapies (PMID: 28251492), in both solid and hematological tumors (PMID: 32148495).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
558 19 19q13.2 NM_021913 Unknown
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