Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol PRKCD
Synonyms ALPS3 | CVID9 | MAY1 | nPKC-delta | PKCD
Gene Description PRKCD, protein kinase C delta, is a serine/threonine-protein kinase that plays a role in both inhibiting and stimulating cell proliferation and apoptosis (PMID: 15054085), and also functions in regulating responses to inflammation (PMID: 29617417). PRKCD signaling has been implicated in tumorigenesis of a variety of human cancers (PMID: 23474764, PMID: 26015399, PMID: 26811494) and a recurrent fusion, LAMTOR1-PRKCD, has been observed in aneurysmal benign fibrous histiocytoma (PMID: 30094855, PMID: 26432191).
Additional content available in CKB BOOST