Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol PRKD1
Synonyms CHDED | PKC-MU | PKCM | PKD | PRKCM
Gene Description PRKD1, protein kinase D1, encodes a serine threonine kinase, which plays a role in the regulation of several cellular processes (PMID: 21357900, PMID: 11978539), including cell proliferation and migration (PMID: 19329994; PMID: 31311827) and intracellular trafficking (PMID: 11978539), and plays a role in Golgi function, regulating vesicle formation (PMID: 23288632). PRKD1 mutations have been identified in polymorphous adenocarcinoma of the salivary gland (PMID: 25240283) and decreased PRKD1 expression has been observed in invasive ductal carcinoma (PMID: 19243594) and androgen-independent prostate cancer (PMID: 12859948).
Additional content available in CKB BOOST