CRACD - Gene Detail
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| Gene Symbol | CRACD | ||||||||||||
| Synonyms | CRAD | KIAA1211 | ||||||||||||
| Gene Description | CRACD, capping protein inhibiting regulator of actin dynamics, inhibits capping proteins, resulting in F-actin polymerization and stabilization of the cadherin-catenin-actin complex, and plays a role in regulation of Wnt signaling and maintenance of epithelial integrity (PMID: 30361697). CRACD mutations have been identified in colorectal cancer (PMID: 30361697) and small cell lung cancer (PMID: 26168399). | ||||||||||||
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