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| Gene Symbol | ARID1B | ||||||||||
| Synonyms | 6A3-5 | BAF250B | BRIGHT | CSS1 | DAN15 | ELD/OSA1 | MRD12 | OSA2 | P250R | SMARCF2 | ||||||||||
| Gene Description | ARID1B, AT-rich interactive domain-containing protein 1B, is a member of the cBaF subunit (PMID: 32303701) of the SWI/SNF chromatin remodeling complex and is involved in cell-cycle activation (PMID: 15170388) and plays a role in neurodevelopment (PMID: 25674384). ARID1B mutations have been identified in several tumor types including, melanoma, gastric, colorectal, liver, neuroblastoma (PMID: 28521285), and pancreatic (PMID: 27737960) and decreased expression has been observed in ovarian clear cell carcinoma (PMID: 29890703). | ||||||||||
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