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PTK6 - Gene Detail

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Gene Symbol PTK6
Synonyms BRK
Gene Description PTK6, protein tyrosine kinase 6, also known as BRK, is a non-receptor tyrosine kinase that plays a role in several cellular processes including cell proliferation, differentiation, and migration (PMID: 25999240, PMID: 20832360). PTK6 overexpression is associated with breast cancer PMID: 25999240), with unclear impact (PMID: 29879184), and has been identified in several additional tumor types (PMID: 20832360), including prostate cancer (PMID: 32211448).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
5753 20 20q13.33 NM_005975 Both: Oncogene and Tumor suppressor (PMID: 30606230)
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