Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol PTK7
Synonyms CCK-4 | CCK4
Gene Description PTK7, protein tyrosine kinase 7 (inactive), is a catalytically-inactive receptor protein tyrosine kinase that is involved in non-canonical Wnt signaling and plays a role in cell migration (PMID: 27438854, PMID: 27499181). Dysregulation of Ptk7 expression has been demonstrated in various tumor types, including colorectal cancer and ovarian cancer (PMID: 27499181, PMID: 25550828) and decreased expression has been reported in invasive ductal breast cancer (PMID: 31933919), while overexpression has been observed in hepatocellular carcinoma (PMID: 31730575) and cervical cancer (PMID: 30944666).
Additional content available in CKB BOOST