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| Gene Symbol | SHROOM3 | ||||||||||
| Synonyms | APXL3 | MSTP013 | SHRM | ShrmL | ||||||||||
| Gene Description | SHROOM3, shroom family member 3, is an actin-binding protein involved in epithelial and neuroepithelial cell remodeling through apical constriction, which requires recruitment of Rho kinases to the apical junction followed by binding to induce constriction (PMID: 18339671, PMID: 22031541, PMID: 25171888). FGFR2-SHROOM3 has been identified in cholangiocarcinoma (PMID: 35176488). | ||||||||||
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