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Gene Symbol ZBTB2
Synonyms ZNF437
Gene Description ZBTB2, zinc finger and BTB domain containing 2, is a member of the POK family transcription factor that regulates the ARF-HDM2-p53-p21 pathway through transcriptional repression (PMID: 19380588). ZBTB2 mutations have been identified in colorectal cancer (PMID: 23684749).
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