CIP2A: Gene Detail - Cancer Knowledgebase (CKB)

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Gene Symbol

CIP2A

Synonyms

KIAA1524 | NOCIVA | p90

Gene Description

CIP2A, cellular inhibitor of PP2A, also known as cancerous inhibitor protein phosphatase 2A (PMID: 31534561), plays a role in regulating PP2A activity thereby indirectly influencing cell cycle progression (PMID: 24214971, PMID: 32071079). CIP2A overexpression and/or amplification have been reported in numerous cancer types (PMID: 24214971, PMID: 25015035), including multiple myeloma (PMID: 32277660), oral squamous cell carcinoma (PMID: 32266176), and esophagogastric junction adenocarcinoma (PMID: 31534561).

NCBI Gene ID	Chromosome	Map Location	Canonical Transcript	Gene Role
57650	3	3q13.13	NM_020890	Unknown

Additional content available in

CKB BOOST

Gene Variants 73
Category Variants 2
Molecular Profiles 72
Evidence 3
Clinical Trials 0

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Genes

(50 Genes)

(2000+ Genes)

Gene Variants

Therapies

Limited

Global Drug Approvals

Drug Classes

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Clinical Trials

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Efficacy Evidence

Variant Tier Coding
(AMP/CAP/ASCO)

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The public access version, CKB CORE™, encompasses 50 cancer-related genes, and every quarter, a select group of genes are exchanged, focusing on a specific theme. Users can search CKB CORE™ via gene and gene variants. The web-based, subscription version, CKB BOOST™, includes more than 2000 cancer-related genes and is designed to interrogate the knowledgebase for specific data attributes while enabling a robust browse-like feature when the desired content is unknown.

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CIP2A - Gene Detail

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