Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol KMT2C
Synonyms HALR | KLEFS2 | MLL3
Gene Description KMT2C, lysine methyltransferase 2C, is a H3K4 histone methyltransferase (PMID: 31128216) that is involved in transcriptional coactivation and functions in chromatin modification (PMID: 31337554) and epigenetic gene regulation (PMID: 31128216). KMT2C mutations are associated with various tumor types (PMID: 24965397; PMID: 23429989; PMID: 24670651), including breast cancer (PMID: 31128216), diffuse-type gastric adenocarcinoma (PMID: 30108106), and urothelial carcinoma (PMID: 30665945).
Additional content available in CKB BOOST