Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol RAD51B
Synonyms R51H2 | RAD51L1 | REC2
Gene Description RAD51B, RAD51 paralog B, plays a role in homologous recombination repair of double-strand DNA breaks (PMID: 21821141, PMID: 32098697). RAD51B mutations are associated with susceptibility to breast cancer (PMID: 24139550, PMID: 29255180) and overexpression has been correlated with a favorable prognosis in non-small cell lung cancer (PMID: 29207658) and a poor prognosis in gastric cancer (PMID: 27651161).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
RAD51B amp no effect
RAD51B del loss of function Olaparib
RAD51B fusion unknown
RAD51B inact mut loss of function Olaparib
RAD51B L103* loss of function - predicted Olaparib
RAD51B loss loss of function Olaparib
RAD51B mutant unknown
RAD51B over exp no effect
RAD51B Q371* unknown
RAD51B R8* loss of function - predicted Olaparib
RAD51B rearrange unknown
RAD51B V207L unknown
RAD51B wild-type no effect
RAD51B Y46* loss of function - predicted Olaparib