Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | RASGRF2 | ||||||||||
| Synonyms | GRF2 | RAS-GRF2 | ||||||||||
| Gene Description | RASGRF2, Ras protein specific guanine nucleotide-releasing factor 2, is a guanine exchange factor that mediates activation of Ras and Rho family members, and plays a role in T-cell response and proliferation (PMID: 21111786). Aberrant methylation of RASGFR2 has been reported in NSCLC (PMID: 16596198), decreased expression has been reported in several tumor types, and mutations in RASGRF2 have identified in breast cancer (PMID: 21111786). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
