Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol ARID4A
Synonyms RBBP-1 | RBBP1 | RBP-1 | RBP1
Gene Description ARID4A, AT-rich interaction domain 4A, is a DNA-binding protein (PMID: 33675746, PMID: 24379399) that associates with the SIN3A corepressor complex (PMID: 16479010, PMID: 18193082) and acts as a coactivator for RB1 and AR (PMID: 23487765), which plays a role in regulation of gene expression (PMID: 33675746, PMID: 16479010), cell growth (PMID: 18193082), and male fertility (PMID: 23487765). Decreased ARID4A expression has been demonstrated in hepatocellular carcinoma (PMID: 35402625).
Additional content available in CKB BOOST