Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol KDM5A
Synonyms NEDEHC | RBBP-2 | RBBP2 | RBP2
Gene Description KDM5A, lysine demethylase 5A, is a Jumonji domain histone demethylase, transcriptional repressor, and epigenetic modifier (PMID: 29602065), that regulates gene transcription through chromatin remodeling to promote cell growth and differentiation (PMID: 30650517). KDM5A overexpression has been reported in a number of cancers including breast cancer (PMID: 22937203) and decreased expression may be prognostic for glioma (PMID: 29324315).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
5927 12 12p13.33 NM_001042603 Oncogene (PMID: 30606230)
Additional content available in CKB BOOST