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AFAP1 - Gene Detail

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Gene Symbol AFAP1
Synonyms AFAP | AFAP-110 | AFAP110
Gene Description AFAP1, actin filament associated protein 1, binds actin and regulates actin filament organization, plays a role in SRC activation, and may function as an adaptor protein for signaling molecules (PMID: 11607843, PMID: 21236256, PMID: 25043309). AFAP1 overexpression has been demonstrated in prostate cancer (PMID: 17885682) and an AFAP1-NTRK2 fusion has been observed in low-grade glioma (PMID: 25204415).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
60312 4 4p16.1 NM_198595 Unknown
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