Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | APOBEC3G | ||||||||||
| Synonyms | A3G | ARCD | ARP-9 | ARP9 | bK150C2.7 | CEM-15 | CEM15 | dJ494G10.1 | MDS019 | ||||||||||
| Gene Description | APOBEC3G, apolipoprotein B mRNA editing enzyme catalytic subunit 3G, is a cytidine deaminase that induces C-to-U mutations in DNA, functioning in host defense against retroviruses and inhibits retrotransposons (PMID: 22001110). APOBEC3G expression correlates with poor prognosis in colon cancer patients with hepatic metastasis (PMID: 24753761), overexpression has been observed in uterine cervical intraepithelial neoplasia (PMID: 28590025), and overexpression in high-grade serous ovarian carcinoma has been associated with a favorable prognosis (PMID: 27016308). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
