RINT1: Gene Detail - Cancer Knowledgebase (CKB)

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Gene Symbol

RINT1

Synonyms

ILFS3 | RINT-1

Gene Description

RINT1, RAD50 interactor 1, encodes a RAD50-binding protein that plays a role in regulating radiation-induced G2/M checkpoint (PMID: 11096100) and membrane trafficking between ER and Golgi (PMID: 16571679, PMID: 23885118, PMID: 17470549). RINT1 copy number gain has been identified in pancreatic ductal adenocarcinoma (PMID: 33531371) and glioblastoma (PMID: 23074196), RINT1 mutations have been identified in colorectal cancer (PMID: 28264000) and hereditary breast cancer (PMID: 39831988).

NCBI Gene ID	Chromosome	Map Location	Canonical Transcript	Gene Role
60561	7	7q22.3	NM_021930	Unknown

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Gene Variants 1
Category Variants 0
Molecular Profiles 1
Evidence 0
Clinical Trials 0

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RINT1 - Gene Detail

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