Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol BCL9
Synonyms LGS
Gene Description BCL9, BCL9 transcription coactivator, is a nuclear transcriptional regulator that regulates the Wnt/beta-catenin (CTNNB1) signaling pathway (PMID: 29786110). Overexpression of BCL9 has been observed in adrenocortical carcinoma (PMID: 29428231), hepatocellular carcinoma (PMID: 28074862), and colon cancer (PMID: 30009824) and a MEF2D-BCL9 fusion has been identified in acute B-Cell precursor lymphoblastic leukemia (PMID: 27019113).
Additional content available in CKB BOOST