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| Gene Symbol | ROCK1 | ||||||||||
| Synonyms | P160ROCK | ROCK-I | ||||||||||
| Gene Description | ROCK1, Rho associated coiled-coil containing protein kinase 1, is a serine/threonine kinase involved in cell contraction, motility, and survival through regulation of actomyosin dynamics (PMID: 24553779) and may play a role in tumorigenesis and metastasis (PMID: 26725045). Decreased expression of Rock1 has been reported in melanoma (PMID: 32234882), while elevated ROCK1 levels in plasma has been observed in pancreatic adenocarcinoma (PMID: 32104251). | ||||||||||
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