RPL10: Gene Detail - Cancer Knowledgebase (CKB)

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Gene Symbol

RPL10

Synonyms

AUTSX5 | DXS648 | DXS648E | L10 | MRXS35 | NOV | QM | uL16

Gene Description

RPL10, ribosomal protein L10, is part of the 60S ribosomal subunit (PMID: 33227977) and plays a role in ribosomal assembly and rotation during the elongation phase of translation (PMID: 24214990, PMID: 30814529), and potentially, regulation of signal transduction pathways involved in various cellular processes (PMID: 12138090, PMID: 33227977). Mutations in RPL10 have been identified in multiple myeloma (PMID: 28428269) and pediatric T-cell acute lymphoblastic leukemia (PMID: 23263491, PMID: 29930300).

NCBI Gene ID	Chromosome	Map Location	Canonical Transcript	Gene Role
6134	X	Xq28	NM_006013	Unknown

Additional content available in

CKB BOOST

Gene Variants 2
Category Variants 0
Molecular Profiles 2
Evidence 0
Clinical Trials 0

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The public access version, CKB CORE™, encompasses 50 cancer-related genes, and every quarter, a select group of genes are exchanged, focusing on a specific theme. Users can search CKB CORE™ via gene and gene variants. The web-based, subscription version, CKB BOOST™, includes more than 2000 cancer-related genes and is designed to interrogate the knowledgebase for specific data attributes while enabling a robust browse-like feature when the desired content is unknown.

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RPL10 - Gene Detail

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