Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | CXCL11 | ||||||||||
| Synonyms | b-R1 | H174 | I-TAC | IP-9 | IP9 | SCYB11 | SCYB9B | ||||||||||
| Gene Description | CXCL11, C-X-C motif chemokine ligand 11, is a member of the CXC chemokine family that is regulated by several IFN family members, including IFN-gamma (PMID: 16081539, PMID: 9625760, PMID: 17142784) and acts through the CXCR3 receptor to recruit immune cells such as T cells, natural killer cells, monocytes, and macrophages during inflammation (PMID: 9625760, PMID: 23012327, PMID: 29207310). CXCL11 has been found to be overexpressed in several cancer types including breast cancer (PMID: 26639244), rhabdomyosarcoma (PMID: 26037167), and prostate adenocarcinoma (PMID: 22247499), and a fusion with AKT2 and CXCL11 has been identified in ovarian cancer (PMID: 29617662). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
