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PRDM1 - Gene Detail

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Gene Symbol PRDM1
Synonyms BLIMP-1 | BLIMP1 | PRDI-BF1
Gene Description PRDM1, PR/SET domain 1, encodes a repressor of beta-interferon gene expression (PMID: 1851123) and regulates plasma cell differentiation (PMID: 27687004). PRDM1 plays a tumor suppressor role in various tumor types (PMID: 22143801; PMID: 20047096) and decreased expression may predict poor survival in colon cancer patients (PMID: 29760071) and may promote metastasis in lung cancer (PMID: 28378641).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
639 6 6q21 NM_001198 Tumor suppressor (PMID: 30606230)
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