PINK1 - Gene Detail

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Gene Symbol PINK1
Synonyms BRPK | PARK6
Gene Description PINK1, PTEN induced kinase 1, is a mitochondria-targeted serine/threonine kinase (PMID: 23533695) involved in mitochondrial membrane potential, morphology (PMID: 21421046), and homeostasis (PMID: 19279012), and plays a role in mitophagy (PMID: 20153330), cell survival (PMID: 16079129, PMID: 19276113, PMID: 21945539), and cell cycle regulation (PMID: 24681957). Increased expression of Pink1 has been observed in lung adenocarcinoma (PMID: 29937472).
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